Signaling silence--breaking ground and spreading out.
نویسندگان
چکیده
Among the persistent mysteries in epigenetics are the criteria by which specific regions of the genome are chosen for deposition of distinguishing chromatin marks. Once a particular region is modified, will the newly acquired epigenetic state spill onto neighboring regions of the genome or be confined to tidy patches? The report by Henderson and Jacobsen in the the previous issue of Genes & Development (1597-1606) addresses these questions while providing insight into the utility of DNA methylation for a eukaryotic genome.
منابع مشابه
مشارکت به چه معنی است؟
Participation has been with us since the inception of living in a family. Participation developed in the matrix of religion and, two centuries ago, opend up its way in political systems of European countries. It supported the democratic principle of people's determining their own destiny. Today, participation is considered a necessity for the total development of not only individuals, but also ...
متن کاملBursty Communication Patterns Facilitate Spreading in a Threshold-Based Epidemic Dynamics
Records of social interactions provide us with new sources of data for understanding how interaction patterns affect collective dynamics. Such human activity patterns are often bursty, i.e., they consist of short periods of intense activity followed by long periods of silence. This burstiness has been shown to affect spreading phenomena; it accelerates epidemic spreading in some cases and slows...
متن کاملSpiral Galaxies as Chiral Objects?
Spiral galaxies show axial symmetry and an intrinsic 2D-chirality. Environmental effects can influence the chirality of originally isolated stellar systems and a progressive loss of chirality can be recognised in the Hubble sequence. We point out a preferential modality for genetic galaxies as in microscopic systems like aminoacids, sugars or neutrinos. This feature could be the remnant of a pr...
متن کاملChanging Knowledge and Attitudes with a Middle School Mental Health Education Curriculum.
PURPOSE: This research tested the effectiveness of a widely used mental health education curriculum in changing knowledge and attitudes about mental illness. METHOD: Middle school students from four schools were provided the Breaking the Silence: Teaching the Next Generation About Mental Illness mental health instruction while students from other classes at the same schools received usual class...
متن کاملEffects of Temperature Fluctuation and Air Aridity on Architecture (Case Study: Dastkand Village Located at Kerman Province)
Constructed upon a height (by footing) or breaking in to the ground, in a building, making a close relation between earth and soil is of great importance. In addition, earth as a prior factor in creation of a shade and residence, plays a crucial role in architecture history. Throughout the different area, earth is paid attention differently: as a source of cool (in China), a source of heat (Cap...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Genes & development
دوره 22 13 شماره
صفحات -
تاریخ انتشار 2008